Measles elimination in Italy: data from laboratory activity 2011-2013.

Tuesday, 29th of March 2016 Print

J Clin Virol. 2015 Mar;64:34-9. doi: 10.1016/j.jcv.2014.12.019. Epub 2014 Dec 31.

Measles elimination in Italy: data from laboratory activity 2011-2013.

Magurano F1 Baggieri M2 Fortuna C3 Bella A4 Filia A5 Rota MC6 Benedetti E7 Bucci P8 Marchi A9 Nicoletti L10.

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Abstract

BACKGROUND:

The European Regional Office of the World Health Organization developed a strategic approach to halt the indigenous transmission of measles in its 53 Member States by 2015 World Health Organization [1]. Many European countries including Italy began the implementation of national programs to reach this goal.

OBJECTIVES:

To describe replicas de relojes españa
and discuss the results of laboratory activity in measles surveillance performed from January 2011 to December 2013 by the Italian National Reference Laboratory for Measles and Rubella.

STUDY DESIGN:

Samples of suspected measles cases were collected from different Italian regions to confirm clinical diagnosis. Anti-measles IgM antibodies detection by Enzyme-Linked Immunosorbent Assay and/or molecular detection by Reverse Transcriptase-Polymerase Chain Reaction assay were performed. Positive samples were sequenced for viral characterization.

RESULTS AND CONCLUSIONS:

According to results from the National Reference Laboratorys activity urine and blood seem to be the best specimens for measles laboratory surveillance. Phylogenetic analysis revealed a co-circulation of the genotypes D4 and D8 during the reviewed period a cluster of B3 and sporadic cases of D9 and H1.

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